TyrosineKinase相关论文
Angiogenesis has been demonstrated to be a basic prerequisite for sustainable growth and proliferation of tumor[1],the l......
STYK1 404 tyrosine residue mutation enhances STYK1 mediated PI3K signaling transductions and human b
STYK1(putative serine/threonine and tyrosine kinase)is a newly identified novel oncogene which belongs to the receptor p......
The combination of a novel Bruton tyrosine kinase (BTK)inhibitor PLS123 and mTOR inhibitor everolimu
目的： Mantle cell lymphoma (MCL) is an aggressive and incurable malignant lymphoma with a median survival of 5 years ......
FLT3 基因即FMS样酪氨酸激酶3(Fms-like tyrosine kinase 3)也称为胎肝激酶2(fetal liver kinase-2)或人干细胞激酶1(human stem c......
目的 探讨Fms样酪氨酸激酶3(FLT3)表达对评估急性髓系白血病(AML)预后的意义.方法 选取AML患者50例,其中核型正常的AML患者20例,核......
AIM: Many growth factors, such as epidermal growth factor(EGF), are associated with the carcinogenesis. EGF plays itsrol......
TO THE EDITORrnHepatocellular carcinoma (HCC) is thought to develop through a multistep process[1]. A long history of v......
AIM: To investigate the antineoplastic potency of the novel insulin-like growth factor 1 receptor (IGF-1R) tyrosine kina......
Prolonged exposure of colon cancer cells to the epidermal growth factor receptor inhibitor gefitinib
AIM: To analyze the biological effects of prolonged in vitro exposure of HT-29 and LoVo colon cancer cell lines to gefit......
Design,synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FG
Fibroblast growth factor receptors(FGFRs)have emerged as promising targets for anticancer therapy.In this study,we synth......
Gene deficiency or pharmacological inhibition of PDCD4-mediated FGR signaling protects against acute
Recent studies have shown that programmed cell death 4(PDCD4)modulates distinct signal transduction pathways in differen......
